Mirabegron 223673-61-8 Inhibitor Neuronal signal
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods
Introduction
Mirabegron, is a beta-3 adrenergic receptor agonist, which stimulates the beta-3 adrenergic receptor and relaxes the detrusor smooth muscle, thereby increasing bladder capacity and is used to treat symptoms of overactive bladder (OAB), such as urge incontinence, urgency, and frequency.
Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine.
Specification (USP/EP)
|
Item |
Specification |
| Appearance | White to off white powder |
|
Identification |
IR, HPLC |
| Water content | NMT 0.5% |
| Residue on ignition | NMT 0.1% |
| Heavy metal | NMT 20ppm |
| Palladium content | NMT 20ppm |
| Optical isomer | NTM 0.5% |
| Related substance | Z-168*: NMT 0.15% |
| SC03610*: NMT 0.15% | |
| Any other unknown impurity: NMT 0.10% | |
| Total impurity: NMT 0.5% | |
| 2-(2-aminothianzol-4-yl) acetic acid | NMT 0.1% |
| Residual solvent | Methanol: NMT 0.3% |
| Ethyl acetate: NMT 0.5% | |
| THF: NMT 0.072% | |
| Benzene: NMT 0.0002% | |
| Toluene: NMT 0.089% | |
| Assay | 98.0% - 102.0% |
| PSD | D (0.5): 10μm - 30μm |
| D (0.9): 20μm - 80μm |
