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Minoxidil was first introduced as an antihypertensive medication and the discovery of its common adverse event, hypertrichosis, led to the development of a topical formulation for promoting hair growth. To date, topical minoxidil is the mainstay treatment for androgenetic alopecia and is used as an off-label treatment for other hair loss conditions. Despite its widespread application, the exact mechanism of action of minoxidil is still not fully understood. In this article, we aim to review and update current information on the pharmacology, mechanism of action, clinical efficacy, and adverse events of topical minoxidil.

Minoxidil also works by increasing the supply of blood and nutrients to your hair follicles helping to strengthen the existing hairs and encouraging them to grow

Minoxidil is the only over- the-counter active ingredient clinically proven to help stop and even reverse hereditary hair loss, by reactivating your inactive hair follicles.

The mechanism by which minoxidil stimulates hair growth is not fully understood, but minoxidil can help reverse the hair loss process of androgenetic alopecia by the following means:

Reverses the miniaturisation of follicles

Increases blood flow around follicles

Stimulates follicle movement to growth phase

Extends each follicle growth phase