China Manufactur standard Fluralaner 864731-61-3 - Moxidectin 113507-06-5 Anti-Parasitics – Neore manufacturers and suppliers

Manufactur standard Fluralaner 864731-61-3 - Moxidectin 113507-06-5 Anti-Parasitics – Neore

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Manufactur standard Fluralaner 864731-61-3 - Moxidectin 113507-06-5 Anti-Parasitics – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Order (MOQ): 25kg
Lead Time: 3 working days
Production capacity: 100kg/month
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: UN2811 6.1/PG 3

Moxidectin

Introduction

Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms (helminths), such as heartworm and intestinal worms, in dogs, cats, horses, cattle and sheep. Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite’s glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite.

Specification (USP)

Item	Specification
Appearance	White or pale yellow amorphous powder
Identification	IR Spectrum of sample corresponds to that of reference substance
Identification	The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay
Water	≤1.3%
Residue on ignition	≤0.2%
Heavy metals	≤20ppm
Assay	92.0-102.0% (anhydrous Substance)
Organic Impurities
Early-eluting impurities	Moxidectin butenyl analog ≤1.5%
	5’-Demethyl Moxidectin ≤0.5%
	Moxidectin Pentenyl Analog ≤1.5%
	Moxidectin 17a-epimer ≤2.5%
	Sum of moxidectin 19-s-17a-ene and moxidectin ethyl isomers (E+F) ≤1.7%
	Mibemycin B analog (moxidectin open ring) ≤1.5%
	Any other individual impurity eluting before milbemycin B analog (moxidectin open ring) ≤0.5%
Late Elutomg impurities	Moxidectin deoxydienea, and 4’-Methylthiomethoxymoxidectin (H+I) ≤ 1.0%
	20b-Methylthiomoxidctin (J) ≤ 0.5%
	20-Nitrobenzoylmoxidectin (K) ≤ 0.5%
	Any other individual impurity eluting after the milbemycin B analog (Moxidectin open ring) ≤ 0.5%
Total organic Impurities	≤7.0%
Solvent residue	Methanol ≤ 3000ppm Methylene Chloride ≤ 300ppm Isopropyl Acetate ≤ 5000ppm N-Heptane ≤ 5000ppm
BHT	0.3%-0.6%

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