Hot-selling Nitazoxanide 55981-09-4 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore
Hot-selling Nitazoxanide 55981-09-4 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 400kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods
Introduction
Tulathromycin, is a broad-spectrum antibacterial agent with antibacterial activity against some gram-positive and Gram-negative bacteria. It especially sensitive to pathogens of respiratory diseases in cattle and pigs, such as Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, histophilus sleep (Haemophilus sleep), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, etc.
The pharmacokinetic characteristics of Tulathromycin are that after single dose administration, it is rapidly absorbed at the injection site, the effective blood concentration is maintained for a long time, the elimination is slow, the apparent distribution volume is large, the bioavailability is high, and the concentration in peripheral tissue is higher than that in plasma. Extensive tissue distribution and good cell permeability are important characteristics of Tulathromycin metabolism. Accumulation in immune cells is also an important feature of Tulathromycin.
Tulathromycin inhibits bacterial protein synthesis by blocking the bacterial peptide transfer process. Due to some important defects of erythromycin, people need another drug to instead of erythromycin urgently. Tulathromycin is a new kind of macrolide semi synthetic antibiotic for animals. It has many advantages, such as low dosage, one-time administration, low residue, animal specific and so on. It not only has the advantages of macrolide drugs, but also has an ultra long half-life which is superior to other macrolide antibiotics. Base on the advantage of maintain effective therapeutic concentration in the body for a long time, it can achieve better bacteriostasis and sterilization.
After extensive clinical application, tulathromycin has obvious therapeutic effect on respiratory diseases of cattle and pigs. Thanks for the excellent antibacterial activity of Tulathromycin like small dosage using, long half-life and one-time administration, it can be used widely.
Tulathromycin is stronger than the macrolides widely used in the market currently, such as tylosin, tilmicosin and florfenicol. Which has huge potential applications.
Attention to be paid that Tulathromycin is relatively safe, without carcinogenicity, teratogenicity and genotoxicity. It will not induce gene mutation, but may produce cardiotoxicity. Need to follow advise of veterinary.
Specification (In House Standard)
|
Item |
Specification |
| Appearance | White or almost white powder |
| Solubility | It is freely soluble in methanol, acetone, and methyl acetate, soluble in ethanol |
| Specific optical rotation | -22° to -26° |
| Identification |
HPLC: retention time of major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the strandard preparation obtained as specified in the assay IR: IR spectrum is consistent with CRS |
| Water | ≤2.5% |
| Residue on ignition | ≤0.10% |
| Heavy metals | ≤20ppm |
| Related substance |
Total impurity ≤6.0% Individual impurity ≤3.0% |
| Bacterial endotoxin | < 2 EU |
| Assay (anhydrous substance) | 95%-103% |
| Residual solvent |
N-Heptane≤5000ppm Dichloromethane ≤600ppm |
| Assay | Content of C41H79N3O12: 95%-103% (On Anydrous substance) |
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To create much more price for clients is our company philosophy; purchaser growing is our working chase for Hot-selling Nitazoxanide 55981-09-4 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore , The product will supply to all over the world, such as: Congo, Nepal, Borussia Dortmund, Many years of work experience, we have realized the importance of providing good quality products and the best before-sales and after-sales services. Most problems between suppliers and clients are due to poor communication. Culturally, suppliers can be reluctant to question things they do not understand. We break down those barriers to ensure you get what you want to the level you expect, when you want it. faster delivery time and the product you want is our Criterion .
By Diego from Sao Paulo - 2018.09.08 17:09
This is a honest and trustworthy company, technology and equipment are very advanced and the prodduct is very adequate, there is no worry in the suppliment.
By Maggie from Victoria - 2017.10.13 10:47
