China Chinese Professional 1077-28-7 - Atipamezole HCL 104075-48-1 Antipyretic-analgesic – Neore manufacturers and suppliers

Chinese Professional 1077-28-7 - Atipamezole HCL 104075-48-1 Antipyretic-analgesic – Neore

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Chinese Professional 1077-28-7 - Atipamezole HCL 104075-48-1 Antipyretic-analgesic – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature
Package material:drum
Package size:25kg/drum
Safety information: Not dangerous goods

Atipamezole HCL

Introduction

Atipamezole hydrochloride, chemical name: 4-(2-ethyl-2-indan) imidazole hydrochloride. Atipamezole hydrochloride competitively inhibits alpha 2 adrenergic receptors, and is an effective α2 adrenergic receptor blocker, which selectively and competitively inhibits α2 adrenergic receptors.

Its pharmacological effects are to reduce sedation, lower blood pressure, increase heartbeat and respiratory rate, and reduce analgesic effects of α2-adrenoceptor blockers, which are mainly used in the recovery of anesthesia after surgery on animals.

Specification (in house standard)

Item	Specification
Appearance	White solid
Identification	IR
Identification of chlorides	Comparable to stand
Melting point	211℃-215℃
Total impuities	≤ 0.1%
Individual impuity	≤0.05%
Loss on drying	≤0.05%2hrs at 105℃
Sulpated ash	0.05% max
Ph of standard solution	5-6
Solution(1% soltion in water)	colorless
Total Heavy metals (As Pb Cd Cr Ni)	≤20ppm
Residual solvents	Acetone<5000ppm
	Methylbenzene<890ppm
	Thf<720ppm
	Methanol<3000ppm
	Dichloromethane<600ppm
	Ethyl acetate<5000ppm
	N-hexane<290ppm
	Ethyl alcohol<5000ppm
Purity (HPLC)	≥99%

Specification Injection grade

Item	Specification
Appearance	Yellow to orange powderodorless.
Identification	IR, HPLC
Residue on ignition	≤0.5%
Related substances
At 303nm	Amphotericin A ≤2.0%
At 303nm	Individual unknown impurity ≤1.0%
At 383nm	Amphotericin X1 ≤4.0%
At 383nm	Individual unknown impurity ≤2.0%
Total impurities	≤15.0%
Residual solvents	Acetone ≤0.5%
Residual solvents	Methanol ≤0.3%
Microbiological limit	Aerobic microbial count ≤1000cfu/g
	Molds & yeasts ≤100cfu/g
	Escherichia coli Absent in 1g
Bacterial endotoxins	<1.0EU/mg
Assay	≥850 amphotericin B units/mg, calculated on the dried basis

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