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Best Price on Doramectin 117704-25-3 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore

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Best Price on Doramectin 117704-25-3 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 400kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods

Tulathromycin

Introduction

Tulathromycin, is a broad-spectrum antibacterial agent with antibacterial activity against some gram-positive and Gram-negative bacteria. It especially sensitive to pathogens of respiratory diseases in cattle and pigs, such as Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, histophilus sleep (Haemophilus sleep), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, etc.

The pharmacokinetic characteristics of Tulathromycin are that after single dose administration, it is rapidly absorbed at the injection site, the effective blood concentration is maintained for a long time, the elimination is slow, the apparent distribution volume is large, the bioavailability is high, and the concentration in peripheral tissue is higher than that in plasma. Extensive tissue distribution and good cell permeability are important characteristics of Tulathromycin metabolism. Accumulation in immune cells is also an important feature of Tulathromycin.

Tulathromycin inhibits bacterial protein synthesis by blocking the bacterial peptide transfer process. Due to some important defects of erythromycin, people need another drug to instead of erythromycin urgently. Tulathromycin is a new kind of macrolide semi synthetic antibiotic for animals. It has many advantages, such as low dosage, one-time administration, low residue, animal specific and so on. It not only has the advantages of macrolide drugs, but also has an ultra long half-life which is superior to other macrolide antibiotics. Base on the advantage of maintain effective therapeutic concentration in the body for a long time, it can achieve better bacteriostasis and sterilization.

After extensive clinical application, tulathromycin has obvious therapeutic effect on respiratory diseases of cattle and pigs. Thanks for the excellent antibacterial activity of Tulathromycin like small dosage using, long half-life and one-time administration, it can be used widely.

Tulathromycin is stronger than the macrolides widely used in the market currently, such as tylosin, tilmicosin and florfenicol. Which has huge potential applications.

Attention to be paid that Tulathromycin is relatively safe, without carcinogenicity, teratogenicity and genotoxicity. It will not induce gene mutation, but may produce cardiotoxicity. Need to follow advise of veterinary.

Specification (In House Standard)

Item

Specification

Appearance White or almost white powder
Solubility It is freely soluble in methanol, acetone, and methyl acetate, soluble in ethanol
Specific optical rotation -22° to -26°
Identification HPLC: retention time of major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the strandard preparation obtained as specified in the assay
IR: IR spectrum is consistent with CRS
Water ≤2.5%
Residue on ignition ≤0.10%
Heavy metals ≤20ppm
Related substance Total impurity ≤6.0%
Individual impurity ≤3.0%
Bacterial endotoxin < 2 EU
Assay (anhydrous substance) 95%-103%
Residual solvent N-Heptane≤5000ppm
Dichloromethane ≤600ppm
Assay Content of C41H79N3O12: 95%-103% (On Anydrous substance)

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The key to our success is "Good Product Excellent, Reasonable Rate and Efficient Service" for Best Price on Doramectin 117704-25-3 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore , The product will supply to all over the world, such as: Estonia, Leicester, Nigeria, our qualify products have good reputation from the world as its most competive price and our most advantage of after-sale service to the clients.we hope we can provide a safe, environmental products and super service to our clients from all of the world and establish strategic partnership with them by our professional standards and unremitting efforts.
  • In China, we have many partners, this company is the most satisfying to us, reliable quality and good credit, it is worth appreciation.
    5 Stars By Diego from Niger - 2017.06.29 18:55
    It's really lucky to find such a professional and responsible manufacturer, the product quality is good and delivery is timely, very nice.
    5 Stars By Doris from Amsterdam - 2018.12.05 13:53