2022 China New Design L-Carnosine - Tacrolimus monohydrate 109581-93-3 Antibiotic – Neore
2022 China New Design L-Carnosine - Tacrolimus monohydrate 109581-93-3 Antibiotic – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 1kg/month
Order(MOQ): 1g
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: vial, bottle
Package size: 1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
Safety information: UN 2811 6.1/PG 3
Introduction
Tacrolimus, is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. It can be used to treat dry eye syndrome in cats and dogs.
Tacrolimus inhibits calcineurin, which is involved in the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, as part of the body’s learned (or adaptive) immune response.
Specification (USP43)
Item |
Specification |
Appearance |
White or almost white crystalline powder |
Identification |
IR, HPLC |
Solubility |
Very soluble in methanol, freely soluble in N,N dimethylformamide and in alcohol, practically in soluble in water. |
Residue on ignition |
≤0.10 % |
Organic impurities (procedure-2) |
Ascomycin 19-epimer ≤0.10 % |
Ascomycin ≤0.50 % |
|
Desmethyl tacrolimus ≤0.10 % |
|
Tacrolimus 8-epimer ≤0.15 % |
|
Tacrolimus 8-propyl analog ≤0.15 % |
|
Unknown impurity -I ≤0.10 % |
|
Unknown impurity -II ≤0.10 % |
|
Unknown impurity -III ≤0.10 % |
|
Total impurities ≤1.00 % |
|
Optical rotation (on as is basis) (10mg/ml in N,Ndimethylformamide) |
-110.0° ~ -115.0° |
Water content (by KF) |
≤4.0% |
Residual solvents (by GC) |
Acetone ≤1000ppm (In-house) |
Di-isopropyl ether ≤100ppm (In-house) |
|
Ethyl ether ≤5000ppm |
|
Acetonitrile ≤410ppm |
|
Toluene ≤890ppm |
|
Hexane ≤290ppm |
|
Microbial test (in house) |
Total aerobic microbial count ≤100cfu/gm |
Total yeast and mould count ≤10cfu/gm |
|
Specified organisms (Pathogens) (E.coil, salmonella sps., S.aureus. Pseudomonas aeruginosa) should absent |
|
Assay (by HPLC) (on anhydrous and solvent free basis) |
98%~102% |
Product detail pictures:
Related Product Guide:
Fast and very good quotations, informed advisers to help you choose the correct merchandise that suits all your preferences, a short creation time, responsible excellent command and different companies for paying and shipping affairs for 2022 China New Design L-Carnosine - Tacrolimus monohydrate 109581-93-3 Antibiotic – Neore , The product will supply to all over the world, such as: Hamburg, Qatar, Swiss, Our company warmly invites domestic and overseas customers to come and negotiate business with us. Allow us to join hands to create a brilliant tomorrow! We've been looking forward to cooperating with you sincerely to achieve a win-win situation. We promise to try our best to deliver you with high quality and efficient services.
By John biddlestone from Netherlands - 2017.03.28 16:34
After the signing of the contract, we received satisfactory goods in a short term, this is a commendable manufacturer.
By Riva from Marseille - 2017.08.28 16:02